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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTN4
All Species:
33.94
Human Site:
S488
Identified Species:
82.96
UniProt:
O43707
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43707
NP_004915.2
911
104854
S488
N
E
L
D
Y
Y
D
S
H
N
V
N
T
R
C
Chimpanzee
Pan troglodytes
XP_510027
892
103041
S469
N
E
L
D
Y
Y
D
S
P
S
V
N
A
R
C
Rhesus Macaque
Macaca mulatta
XP_001083712
906
104307
S488
N
E
L
D
Y
Y
D
S
H
N
V
N
T
R
C
Dog
Lupus familis
XP_853410
911
104912
S488
N
E
L
D
Y
Y
D
S
H
N
V
N
T
R
C
Cat
Felis silvestris
Mouse
Mus musculus
P57780
912
104959
S489
N
E
L
D
Y
Y
D
S
H
N
V
N
T
R
C
Rat
Rattus norvegicus
Q9QXQ0
911
104897
S488
N
E
L
D
Y
Y
D
S
H
N
V
N
T
R
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90734
904
104189
S481
N
E
L
D
Y
Y
D
S
P
S
V
N
A
R
C
Frog
Xenopus laevis
NP_001087030
904
104150
S481
N
E
L
D
Y
Y
D
S
P
S
V
N
A
R
C
Zebra Danio
Brachydanio rerio
NP_955880
901
103767
S478
N
E
L
D
Y
Y
D
S
P
S
V
N
A
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18091
924
107001
C501
N
T
L
E
Y
H
D
C
V
S
V
N
A
R
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
97.9
99
N.A.
98.4
98.4
N.A.
N.A.
92.4
89.9
86.3
N.A.
66.9
N.A.
N.A.
N.A.
Protein Similarity:
100
90
98.5
99.6
N.A.
99.2
99.3
N.A.
N.A.
95.8
94.1
92.7
N.A.
81.2
N.A.
N.A.
N.A.
P-Site Identity:
100
80
100
100
N.A.
100
100
N.A.
N.A.
80
80
80
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
N.A.
86.6
86.6
86.6
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
100
% C
% Asp:
0
0
0
90
0
0
100
0
0
0
0
0
0
0
0
% D
% Glu:
0
90
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
50
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
100
0
0
0
0
0
0
0
0
50
0
100
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% R
% Ser:
0
0
0
0
0
0
0
90
0
50
0
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
50
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
100
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
100
90
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _